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Mesothelioma and Asbestos Exposure Exposure to asbestos is the reason mesothelioma. Exposure to asbestos can occur at work or at home. Symptoms of pleural mesothelioma include chest pain, coughing and dry cough. Other signs include abdominal pain, a buildup fluid and testicular cancer. There are four types of mesothelioma. Pleural mesothelioma, the most commonly encountered kind. Occupational Exposure Mesothelioma, a cancer affecting the linings of certain organs such as the lungs and the abdomen, is typically caused by asbestos exposure. This toxic mineral is used in a variety of industries, and when it breaks down, creates fine dust that can be inhaled or consumed. In the past, asbestos exposure was high in a variety of occupations. These include asbestos insulators, plumbers, electricians shipyard workers, and producers of automotive parts, brake pads, clutches and packing. Construction workers exposed to asbestos through their construction materials or when building new structures, are at a high chance of being exposed. Mesothelioma occurs when mesothelial cells develop mutations and begin to expand out of control, and eventually form tumors that can spread throughout the body. Mesothelioma typically develops in the lungs or abdomen however it can also be found in other organs, like the testicles and heart. There are different types of mesothelioma. Each type is named after the organ that it affects. Symptoms of mesothelioma usually appear 30 to 50 year after the initial exposure. Mesothelioma is a rare type of cancer that is difficult to recognize. It could take years before symptoms show up. Asbestos patients need medical assistance to get a diagnosis and receive treatment. Non-occupational asbestos exposure may increase the risk of mesothelioma. Secondary or indirect asbestos exposure occurs when people come in contact with fibers of asbestos through contaminated clothing and household items. These exposures can occur when family members wash and clean the clothes of a worker or when people live near an industrial asbestos source. A few studies that are based on population-based case-control have examined asbestos exposure in para-occupational settings and mesothelioma risk. One study revealed a significant mesothelioma risk in the communities that are near an asbestos cement factory located in Casale Monferrato, northwest Italy. The authors attributed the rise in mesothelioma-related risk to the residential proximity of the plant, and airborne exposure from the use asbestos cement products on nearby roads and structures. Similar results have been reported in other community-based studies that have clearly identified industrial sources for exposure to para-occupational hazards. These studies can be a challenge. Some studies have had difficulty separating out individuals with known occupational or para-occupational exposure to asbestos, which can lead to errors in assessing the mesothelioma dangers of these individuals. Environmental Exposure Asbestos is made up of an assortment of minerals that are made up of microscopic fibers. Asbestos is resistant to electricity, chemicals, and fire. It has been utilized in a variety of industrial processes and products. Mesothelioma is more likely to develop in those who work with asbestos or are exposed to it in different ways. This includes asbestos miners and shipyard workers as well as asbestos-cement producers and insulation. However, mesothelioma may be brought home on hair and clothing worn by workers which puts their family members at risk, too. Occupational exposure to asbestos is the main cause of mesothelioma. However, a tiny number of cases have been identified in people who have had non-occupational (para-occupational) exposure to asbestos. In these instances asbestos fibers could be ingested into the lungs or into the digestive tract through contaminated air or by eating a person's contaminated food. Typically, these mesothelioma cases have occurred in the family members of asbestos-exposed workers. A mesothelioma diagnosis typically occurs years after asbestos exposure and the tumors are typically located in the chest or abdomen. The most common mesothelioma type is called pleural mesothelioma that affects the chest cavity's lining. The peritoneum is the lining of your abdominal cavity and is the second most commonly-used mesothelioma type that is malignant. The mesothelioma cancer cells are classified as epithelioid and sarcomatoid. Epithelioid mesothelioma accounts for about 60% to 70% of all mesothelioma cases, and generally has the best results. Sarcomatoid mesothelioma can be more aggressive and has a lower prognosis. Biphasic mesothelioma is a type that occurs in 10% to 15% of patients. It is composed of epithelioid cell with sarcomatoid cells. Men are more likely to develop mesothelioma than females. The majority of patients diagnosed with the disease were exposed to asbestos while at work. However, the reasons for this gender difference remain unclear. It could be due to the higher percentage of men employed in fields that typically used asbestos, like manufacturing and construction. Numerous studies have revealed that mesothelioma is more prevalent in communities that have multiple asbestos-related sources. One study of mesothelioma in 70 communities that were contaminated with Vermiculite from the Libby Asbestos Mine in Montana found that people who lived within 2000m of these facilities had a greater chance of developing mesothelioma. Genetic Predisposition In certain cases, genetics may play a role in mesothelioma. The disease is believed to be caused by hereditary changes in genes that affect DNA repair mechanisms. Researchers have identified genes that might cause mesothelioma to develop. Certain studies have found that people with a history of mesothelioma to be more likely to develop it than people who don't. The cause of the cause of the disease isn't completely understood. It is well-known that environmental and occupational asbestos exposure can trigger mesothelioma. Not all people exposed to asbestos will develop mesothelioma. A lot of mesothelioma sufferers have no known asbestos exposure, and some people who have a lot of occupational exposure do not get the disease. These patients are likely to be affected by genetic mutations that hinder the repair of DNA. A genetic mesothelioma test can be used to identify if an individual has the hereditary mutations in the gene that could increase their risk of developing the disease. A doctor can carry out the test using a sample of blood or saliva. The sample is sent to a laboratory for analysis. In most cases the results of the test are available within two weeks. Some families with multiple mesothelioma cases carry a gene mutation in BAP1. This gene is involved in the repair of damaged DNA. The mutation can cause cells to overproduce cancerous cells, which can then spread to other parts of the body and cause mesothelioma. Genetic mesothelioma testing is a helpful method to identify asbestos-related diseases. They can assist doctors understand the mesothelioma's causes and formulate more effective treatment plans. The risk of exposure to asbestos is preventable by avoiding occupational and environmental exposure to asbestos. Individuals who have mesothelioma in their family should talk to their physicians about the potential genetic risk. Some people can benefit from participating in mesothelioma-related testing programs that require a cheek swab or blood sample. In these programs, a patient's mesothelioma prognosis is evaluated by a team of experts. The patient's mesothelioma treatment plan is then designed based on their specific diagnosis. Treatment Mesothelioma occurs when tiny asbestos fibers get into the body, causing damage that can lead to cancer. Asbestos exposure can happen in various ways, including when workers take asbestos pieces apart to remove it or when people take the fibers home on their clothes and skin after they leave work. These fibers can get into the stomach and lungs which can cause irritation that leads to cancer. Symptoms of mesothelioma don't appear for 20 to 50 years after exposure, so it is crucial that those who may have been exposed to asbestos visit their doctor as soon as they can. The majority of mesothelioma cases are males, and the disease most often affects the linings of the lungs. Palatine asbestos lawsuit of mesothelioma can be found in the lining of the stomach the peritoneum, the lining of the heart or testicles. Like all types of cancer, mesothelioma develops when cells begin to expand beyond their limits and develop into a tumor. The abnormal cells can spread to other areas of the body, and eventually result in more cancerous tumors. Researchers aren't sure of the cause of mesothelioma. However, they are aware that exposure to asbestos is a significant risk factor. Patients with mesothelioma are often treated with chemotherapy and surgical procedures in order to slow down the progression of their condition. People who have been exposed to asbestos should be aware of their health and consult with their doctors about the work history. Mesothelioma patients should undergo regular tests for signs of asbestos and other potential problems. The most common mesothelioma symptoms include pain and the buildup of fluid around the lungs. Other symptoms can include coughing, chest pain, the sensation of pressure on the abdomen and chest, abdominal swelling, difficulty breathing weight loss and fatigue, as well as fever. Mesothelioma may have symptoms that are similar to those of other illnesses and conditions. X-rays and blood tests will confirm the diagnosis. Some mesothelioma patients might have genetic mutations in their DNA, which increase the likelihood of developing this disease. These patients should speak to their physician about genetic counselling.